New Approach Methodologies (NAMs): The TTC Concept

Web Seminar in cooperation with Cosmetics Europe – bookable at any time

Seminar fee: 200 EUR + VAT

Seminar-TTC

Introduction

The cosmetics industry has a long-standing and ongoing commitment to replacing animal testing. It has invested in several major initiatives and is one of the key players in developing and raising the profile of New Approach Methodologies (NAMs) and Next Generation Risk Assessment (NGRA) at international regulatory level as well as encouraging its use in the cosmetics industry.

To increase understanding of these innovative alternative approaches that can be used for safety assessment of cosmetic ingredients and finished products and to grow confidence in them, DGK/IKW and Cosmetics Europe will hold a series of webinars drawing on its ongoing research activities supported under the Long Range Science Strategy (LRSS) programme. Industry experts will be invited to provide an overview of the use of NAMs for safety assessment and some of the recent work in this area.

This first webinar will address concepts such as Threshold of Toxicological Concern (TTC) and inhalation TTC for risk assessment of substances with little or even no experimental data. Furthermore, we will also look into how exposure based waiving can be applied within the skin sensitisation NGRA framework.

(Recording of 23 June 2021)

Program

No Title Speaker
1 The TTC Concept and its Application in the Cosmetics Safety Assessment Dr Dagmar Bury (L’Oréal, France)
Not available in the recorded web seminar: Transforming Thresholds of Toxicological Concern (TTCs) to Internal TTC: Why Internal Exposure Matters and How We Will Get There Dr Corie Ellison (Procter & Gamble, USA)
2 Using the Threshold of Toxicological Concern as an exposure-based waiving approach for inhalation exposure safety assessment Dr Nikaeta Sadekar (Research Institute for Fragrance Materials, USA)
3 SCCS Notes of Guidance, 11th Revision Dr Arianna Giusti (Cosmetics Europe, Belgium)
4a/b Skin Sensitisation – Next Generation Risk Assessment and exposure-based waiving Dr Mustafa Varçin (Cosmetics Europe, Belgium)

Dr Detlef Keller (Henkel, Germany)

Duration: 01:50 hrs video training

Speakers

Registration

Web Seminar in cooperation with Cosmetics Europe:
New Approach Methodologies (NAMs): The TTC Concept

(bookable at any time)

Seminar fee: 200 EUR + VAT

 

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